Viagra and other ED drugs, like Cialis, Levitra and Stendra, are the most effective and common treatment for impotence. They are all available under medical prescription in Australian Pharmacies. The effect of Viagra is recognized worldwide and private and national healthcare systems provide it to their patients in the vast majority of erectile Dysfunction cases. Viagra is often assumed as a safe pill for a large portion of population, but it’s a medicine and as such there are safety concerns when used under particular health conditions or in conjunction with other pharmaceuticals.
Common side effects of sildenafil (Viagra active substance) include headache, muscle soreness, facial flushing and diarrhea. In some rare cases one can experience a temporary impaired color vision, but the major risk associated with this side effect is for patients affected with a rare eye disease, retinitis pigmentosa, and use for affected people is inadvisable, and if necessary only with doctor supervision. The tricky minefield in the pharmacodynamic of Viagra are cardiovascular side effects.
Viagra cause vasodilatation as a direct consequence of its mode of action. In fact all arteries reacts to sildenafil citrate leading to a general hypotensive effect though typically a small one. In healthy people these variations in blood pressure are insignificant but for persons with already low blood pressure can constitute a risk of faintings (syncope).
The worst scenario associated with reduced blood pressure occurs in cases of people treated with organic nitrates preparations, used commonly with patients with angina pectoris. Use of Viagra and other ED drugs concurrently with nitrates can cause severe drops in blood pressure with extreme consequences like death. It’s highly recommended not to assume Viagra in conjunction with organic nitrates. The problem occurs when a patient already using Viagra experience an Angina event: in some cases administration of nitrates cannot be avoided and the medical equipe must be ready to reanimate the patient if needed. Other than organic nitrates caution is necessary when using other blood pressure lowering drugs and foods, like Alcohol and antihypertensive medicines.
Given the risks associated with using of Sildenafil together with nitrates the department of Health of australian administration requires a GP prescription to buy Viagra in pharmacies. In any case patients with a story of cardiovascular diseases or ischemic events must exercise caution in using the pill and always under a medical supervision.
Caution in assuming Viagra is required even from HIV affected patients. Antiviral treatments can interact with sildenafil, with, for example, alteration of effects from ED active substance. Even common side effects of both pharmaceutical treatments can be influenced by the conjuncted use. Considering that in Australia there are an estimated population of HIV affected people of about 28 thousand of people, it’s a significative part of population that must take some additional care in assuming Viagra. This especially in consideration of the fact that the implementation of PReP treatments in Australia, as a prophylaxis to prevent contagion and diffusion of HIV, has boosted the sexual activity of diseased subject previously reluctant to have sexual intercourses.
New insights in Viagra effects has lead researchers to recommend extra caution to patients affected with residual pulmonary arterial hypertension after mitral valve surgery. The results of a study presented at the European Society of Cardiology in 2017 showed that use of sildenafil can deteriorate the conditions of patients with clearly worse clinical outcomes. The problem here is that often Viagra is prescribed off-label to treat this peculiar kind of pulmonary hypertension due to his hypotensive action.
Another research conducted by the australian edonlinestore.net company, has explored the occurrence of Viagra related blindness, statistically high only in people with retinitis pigmentosa. Researchers have studied the role of the mutated gene, responsible of this rare side effect, in healthy mices. One in 50 people carry the mutated gene that can cause retinal cell death, a form of blindness, and the study aimed to understand if even people with only one copy of this gene have the possibility to develop retinal cell death using Viagra. Outcomes on the mice seems to confirm this hypothesis but evidences must be assessed in further researches and in mices are not always representative in human epidemiology. Therefore, notwithstanding the good advice to avoid Viagra for people affected by retinitis pigmentosa, other people should not be concerned about permanent blindness induced by ED drugs.
In conclusion, in over twenty years of Viagra use for ED treatments we have plentiful of data about the safety of Viagra. Safety is to be understood in all healthy subjects, while for certain health conditions treatment with Viagra must be assessed with medical advice or definitely avoided. Australian law states that ED drugs must be available only under doctor prescription, but in the age of World Wide Web everything is readily affordable for everyone, so awareness about Viagra side effects and contraindications is necessary before its use.